Antitussive agent.

10ml of syrup contains: active principle: Butamirate citrate (DCl; butamirati dihydrogenocitras) 15mg; excipients, Saccharinum natricum, Vanillinum; Conserv.,E 210.

Sinecod syrup contains the sweetener saccharine and may thus be used by diabetics.



What is Sinecod used for?
When must Sinecod not be used?
What precautions are required when using Sinecod?
Can Sinecod be used during pregnancy or when breast feeding?
What undesirable side effects can Sinecod have?
Dosage
Drug Interaction
Remarks

What is Sinecod used for?
Butamirate citrate, the only active substance in Sinecod syrup, is a central cough suppressant which is chemically and pharmacologically unrelated to the opium alkaloids. In addition to a directly antitussive effect, it also tends to reduce airway resistance, evidenced by an improvement in spirometer values.

Owing to its distinct cough-suppressant and broncho-spasmolytic effect, Sinecod syrup brings about rapid improvement of spirometric and blood gas values in addition to effective cough relief.

Butamirate has a broad therapeutic margin, thus, Sinecod syrup is well tolerated even at high doses and hence, well suited for the reliable treatment of cough in adults and children.

Sinecod syrup is indicated for acute cough due to a variety of causes; suppression of preoperative and postoperative cough in surgery and bronchoscopy; whooping cough.
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When must Sinecod not be used?
When the patient is hypersensitive to the active substance.
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What precautions are required when using Sinecod?
No special precautions.


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Can Sinecod be used during pregnancy or when breast feeding?
No adverse fetal effects have been observed in animal reproduction studies, and there have been no controlled studies in pregnant women. Sinecod syrup should therefore not be used during the first trimester of pregnancy. During the remainder of pregnancy, Sinecod syrup can be used if definitely indicated by a physician but with caution.

As a general rule, for safety reasons, in the absence of data on elimination of the active substance in breast milk, the benefits of Sinecod syrup administration during breast feeding should be carefully weighed against the risks.
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What undesirable side effects can Sinecod have?
Tolerance of Sinecod syrup is good. Adverse reactions such as rash, nausea, diarrhoea and vertigo have been observed in a few rare cases (a total of approximately 1% of treated cases in clinical trials), resolving after dose reduction or treatment withdrawal.
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Dosage:

Children over 3 years of age, 1 teaspoon (5ml) 3 times a day; over 6 years, 2 teaspoons 3 times a day; over 12 years, 1 tablespoon (15ml) 3 times a day.

Adults, 1 tablespoon 4 times a day.


Overdosage:
Accidental overdosage with Sinecod syrup can cause the following symptoms: drowsiness, nausea, vomiting, diarrhoea, loss of balance and hypotension. Standard emergency procedures should be followed: activated charcoal, saline laxatives and standard cardiorespiratory resuscitation.
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Drug Interaction:
None have been observed to date.
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Remarks:
Protect from heat. Store below 30°C .

Packaging:
Bottle of 100 ml
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