Topical antifungal agent
Lamisil contains 1% of terbinafine hydrochloride 10mg per 1g .
What is Lamisil used for?
When must Lamisil not be used?
What precautions are required when using Lamisil?
Can Lamisil be used during pregnancy or when breast feeding?
What undesirable side effects can Lamisil have?
Dosage
Drug Interaction
Remarks
What is Lamisil used for?
Lamisil is indicated for the treatment of interdigital-type pedis (athlete’s foot), tinea cruris (jock itch) and tinea corporis (ringworm) caused by Trichophyton (e.g. T. rubrum, T. mentagrophytes, T. verruccosum, T. violaceum), Microsporum canis and Epidermophyton floccosum.
Lamisil is also indicated for Yeast infections of the skin principally those caused by genus candida (e.g. candida albicans), pityriasis (tinea) versicolor due to pityrosporum orbiculate (also known as malassezia furfur).
Terbinafine hydrochloride, the active substance in Lamisil, is a synthetic allylamine derivative. Terbinafine hydrochloride is hypothesized to act by inhibiting the epoxidation of squalene, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes, resulting in fungal cell death.
Terbinafine hydrochloride, when given topically, has a rapid onset of action and can be effective with short treatment duration.
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When must Lamisil not be used?
Hypersensitivity to terbinafine and any of its excipients.
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What precautions are required when using Lamisil ?
Lamisil is for external use only.
Contact with eyes should be avoided.
Lamisil should be kept out of reach from children.
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Can Lamisil be used during pregnancy or when breast feeding?
Foetal toxicity and fertility studies in animals suggest no adverse effects.
In topical treatment, the small amounts absorbed through the skin are unlikely to affect the infant.
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What undesirable side effects can Lamisil have?
Redness, itching or stinging occasionally occur at the site of application; however, treatment rarely has to be discontinued for this reason. If you experience an increase in the redness, itching, burning, blistering, swelling or oozing of the skin, discontinue use of product and consult medical advise.
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What else needs to be taken into account?
Dosage:
Lamisil can be applied once or twice daily. Cleanse and dry the affected areas thoroughly before treating with Lamisil. Apply to the affected skin and surrounding area in a thin layer and rub in lightly. In cae of intertriginout infections (submammary, interdigital, intergluteal iujuinal) the application may be covered with gauze specially at night.
Likely duration of treatment:
Tinea corporis, cruris: 1 week
Tinea pedis: 1 week
Cutaneaous candidiasis: 1 week
Pityrtasis versicolor: 1 week
(Spray,Derm Gel)
Relief of clinical symptoms usually occurs within a few days. Irregular use or premature discontinuation of treatment carries the risk of recurrence. If there are no signs of improvement after two weeks the diagnosis should be verified.
Overdosage:
No cases of overdosage have been reported with Lamisil.
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Drug Interaction:
No interactions known.
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Remarks:
Packaging:
Tube of 15g 1% .
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